Professor Buch is a Professor of Rheumatology, Director of Experimental Medicine at the Centre for Musculoskeletal Research, University of Manchester, NIHR Senior Investigator and lead on the ‘Advanced Diagnostics & Therapeutics Catalyst’ cluster at the NIHR Manchester Biomedical Research Centre. Professor Buch’s areas of research interest include clinical and experimental research in targeted therapies in RA, systemic sclerosis, and cardiovascular pathology in immune-mediated inflammatory disease – employing multi-modal approaches to phenotype cardiovascular involvement in people with IMIDs and examine the effect of targeted therapies of IMIDs on cardiovascular pathology.